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Alamycin

Alamycin

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    Introduction

    Presentation

    A sterile aqueous solution containing Oxytetracycline Dihydrate Ph.Eur equivalent to 300 mg/ml of oxytetracycline base.

    Uses

    Alamycin LA 300 is a broad spectrum antibiotic indicated for use in the treatment of conditions caused by, or associated with, organisms sensitive to oxytetracycline in cattle, sheep and pigs. A wide range of Gram-positive and Gram-negative bacteria, including Bordetella bronchiseptica, Actinomyces pyogenes, Erysipelothrix rhusiopathiae, Pasteurella spp., Staphylococcus spp., and Streptococcus spp., are sensitive to oxytetracycline. Certain mycoplasma, rickettsiae, protozoa and chlamydia are also sensitive to oxytetracycline.

    Alamycin LA 300 may be used in the treatment and control of a wide range of common systemic, respiratory, urinary and local infections caused by oxytetracycline sensitive organisms. Specific indications for Alamycin LA 300 would therefore include: pasteurellosis, pneumonia, atrophic rhinitis, erysipelas, joint-ill/navel ill, summer mastitis in cows, ovine keratoconjunctivitis (pink-eye) and the control of enzootic abortion in sheep.

    Dosage & administration

    Alamycin LA 300 is specifically formulated to provide a prolonged action, resulting in sustained antibacterial activity. Following intramuscular administration effective blood levels persist for 3 - 4 days at a dose rate of 20 mg/kg and for 5 - 6 days at a dose rate of 30 mg/kg. Maximum blood levels are achieved between 4 - 6 hours following administration making Alamycin LA 300 suitable for the treatment of acute infections.

    Administer by deep intramuscular injection to cattle, sheep and pigs for the treatment and control of conditions caused by organisms sensitive to the action of oxytetracycline.

    Alamycin LA 300 can be administered at the standard dose of 20 mg/kg in order to obtain 3 to 4 days duration of activity or at the high dose of 30 mg/kg for prolonged duration of activity (i.e. activity maintained for 5 to 6 days). Use aseptic injection technique.

    Cattle, Sheep and pigsStandard Dose20mg/kg (1ml/15kg)
     High Dose30mg/kg (1ml/10kg)

    Maximum recommended dosage at one site:

    Cattle15ml
    Pigs10 ml
    Sheep5 ml
    Piglets1 Day - 0.2 ml
    7 Days - 0.3 ml
    14 Days - 0.4 ml
    21 Days - 0.5 ml
    Over 21 Days - 1 ml/10 kg

    Price comparison

    Contra-indications, warnings, etc.

    Do not dilute Alamycin LA 300.

    Although Alamycin LA 300 is well tolerated, occasionally a slight local reaction of a transient nature may be observed.

    The use of tetracyclines during the period of tooth and bone development, including late pregnancy, may lead to discolouration.

    Oxytetracycline therapy does not completely eliminate chlamydial infection in a flock.

    If concurrent treatment is administered use a separate injection site.

    Pharmaceutical precautions

    Do not store above 25C. Protect from light. Following withdrawal of the first dose use the product within 28 days. Discard unused material. Keep out of reach of children.

    Packaging quantities

    Multi-dose vials of 100ml.

    Further information

    If stored as directed Alamycin LA 300 can be expected to retain its potency for 2 years from the manufacturing date. When the vial has been broached and the contents exposed to air, the solution may darken but the potency will be unchanged.



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